Billionaire Family Office Acquires $65 Million of HeartFlow as Stock Jumps 70% From IPO

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Jonathan Ponciano, The Motley Fool

Sun, November 30, 2025 astatine 4:49 PM CST 5 min read

Tulsa-based Schusterman Interests added 1,939,201 shares of HeartFlow valued astatine $65.3 cardinal successful the 3rd quarter.
The presumption represents 14.9% of the fund's 13F reportable assets nether management.
HeartFlow is present the fund’s fourth-largest holding, reflecting a important caller allocation.
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Tulsa-based Schusterman Interests initiated a caller presumption successful HeartFlow, Inc. (NASDAQ:HTFL), acquiring implicit 1.9 cardinal shares valued astatine $65.3 million, according to a November 14 SEC filing.

Schusterman Interests disclosed a caller presumption successful HeartFlow (NASDAQ:HTFL), acquiring 1.9 cardinal shares during the 3rd quarter, arsenic reported successful its November 14 SEC filing. The involvement was valued astatine $65.3 cardinal arsenic of September 30, bringing HeartFlow into the fund’s portfolio arsenic its fourth-largest holding among six full positions.

Top holdings aft the filing:

NYSE:KRMN: $148 cardinal (33.8% of AUM)
NYSEMKT:RSP: $118.6 cardinal (27.1% of AUM)
NYSEMKT:SPY: $88.3 cardinal (20.2% of AUM)
NASDAQ:HTFL: $65.3 cardinal (14.9% of AUM)
NYSE:PACK: $17 cardinal (3.9% of AUM)

As of Friday, HTFL shares were priced astatine $32.25, up astir 70% from their August IPO terms of $19.

Metric

Value

Price (as of marketplace adjacent Friday)	$32.25
Market Capitalization	$2.7 billion
Revenue (TTM)	$161.9 million
Net Income (TTM)	($125.4 million)

HeartFlow, Inc. is simply a healthcare exertion institution specializing successful advanced, non-invasive diagnostic tools for coronary artery disease. The company’s strategy centers connected leveraging artificial quality and computational modeling to heighten objective decision-making and diligent outcomes. With its scalable level and absorption connected precision diagnostics, HeartFlow aims to differentiate itself successful the competitory aesculapian exertion scenery by delivering actionable insights to healthcare providers globally. It offers a proprietary AI-powered level for non-invasive diagnosis and absorption of coronary artery disease, generating gross chiefly from the HeartFlow Platform and related healthcare accusation services.

A caller disclosure from the billionaire-backed Schusterman household bureau highlights an absorbing ballot of assurance successful a recently nationalist institution gathering defensible exertion successful a large, under-digitized market. HeartFlow, which lone began trading successful August, sits astatine the intersection of AI, cardiology, and precision diagnostics—a operation attracting long-horizon investors adjacent arsenic early-stage medtech valuations stay volatile.

According to the November 14 filing, Schusterman Interests—signed by a managing manager of Charles and Lynn Schusterman Family Investments—initiated a $65.3 cardinal presumption successful HeartFlow during the 3rd quarter, acquiring 1.9 cardinal shares. The household bureau present counts HeartFlow arsenic its fourth-largest holding successful the filing, alongside a caller Karman position. As of September 30, HeartFlow represented 14.9% of the fund’s 13F assets.

HeartFlow shares person climbed astir 70% from their $19 IPO terms pursuing August’s upsized offering, which raised astir $316.7 cardinal successful gross proceeds. Ultimately, for semipermanent investors, the Schusterman determination reflects increasing assurance successful a promising technology—and raises the question of whether HeartFlow’s aboriginal momentum tin construe into durable gross maturation arsenic the level expands.