Mizuho Lowers Price Target on Apellis Pharmaceuticals (APLS) Amid Ongoing Eye Disease Therapy Challenges

5 days ago 8

Sheryar Siddiq

Tue, November 25, 2025 astatine 7:39 AM CST 1 min read

Apellis Pharmaceuticals Inc. (NASDAQ:APLS) ranks among the most oversold biotech stocks to put in. On November 3, Mizuho maintained its Neutral standing for Apellis Pharmaceuticals Inc. (NASDAQ:APLS) and reduced its terms people from $24 to $19. Despite encouraging aboriginal results from Empaveli’s motorboat successful C3G/IC-MPGN indications, Mizuho attributed the revision mostly to ongoing maturation issues with Syfovre, Apellis’ medicine for oculus disease.

In Q3 2025, Syfovre’s gross totaled $150.9 million, a insignificant alteration from $152.0 cardinal successful Q3 2024. Despite this insignificant fall, the institution reported a 4% quarter-over-quarter summation successful injections. Apellis Pharmaceuticals Inc. (NASDAQ:APLS) stated that SYFOVRE retains implicit 60% marketplace stock successful the GA attraction area, with 52% of caller diligent starts successful Q3 2025. Mizuho has chopped its Syfovre gross projections, present projecting a highest yearly gross of astir $800 million, 25–30% little than the statement estimates. Apellis Pharmaceuticals Inc. (NASDAQ:APLS) is simply a commercial-stage biopharmaceutical institution that discovers, develops, and commercializes caller therapeutic compounds to dainty diseases with precocious unmet needs. While we admit the imaginable of APLS arsenic an investment, we judge definite AI stocks connection greater upside imaginable and transportation little downside risk. If you're looking for an highly undervalued AI banal that besides stands to payment importantly from Trump-era tariffs and the onshoring trend, spot our escaped study connected the best short-term AI stock. READ NEXT: 10 Best Magic Formula Stocks for 2025 and 10 Best Retirement Stocks to Buy According to Hedge Funds. Disclosure: None. This nonfiction is primitively published at Insider Monkey.


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