Stock Market Today: Nasdaq, S&P 500 Open Higher to Start Week; Novo Nordisk Plummets After Ozempic Alzheimer's Miss

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Happy Monday. This is TheStreet’s Stock Market Today for Nov. 24, 2025. You tin travel the latest updates connected the marketplace present successful our regular unrecorded blog.

The U.S. markets are present open. The Nasdaq (+1.33%) is starting the week connected beardown footing, trailed by the S&P 500 (+0.75%). Meanwhile, the Russell 2000 (+0.35%) and Dow (+0.25%) are besides up, albeit, bested by immoderate margin.

Updates volition beryllium added present shortly.

Weight nonaccomplishment pills person been floated arsenic a imaginable attraction for everything. However, Alzheimer's is apparently not one of those diseases easy treated by the burgeoning GLP-1 people of drugs.

Novo Nordisk (-10.4%) is plummeting this morning, dragging down shares of Eli Lilly (-1%) aft its value nonaccomplishment pill Ozempic did not "demonstrate a statistically important simplification successful Alzheimer's illness progression" successful a signifier 3 study.

Novo's Executive VP of Research and Development says that they pursued the survey based connected "significant unmet request successful Alzheimer's arsenic good arsenic a fig of indicative information points," but the survey was mostly seen arsenic a long-shot. There are apt different indications wherever the blockbuster cause could beryllium trialed to greater effect, overmuch similar the companies did with value loss.

Aside from the GLP-1 names, present are the movers for today, per MarketWatch:

Inspire Medical Systems (+18.5%) is jumping aft an upgrade from Stifel, which bumped the company's stock people to $110 amid higher reimbursements. It's joined by Ingredion (+9.8%), which has faced antagonistic quality successful caller weeks but announced a woody to exit its involvement successful a associated task with spouse Amyris. Finally, Centene (+8.3%) is jumping amid caller expert upgrades and hopes of a caller Republican wellness attraction program which volition widen Obamacare subsidies for astatine slightest 2 years.

On the different extremity of the market, Novocure (-7.3%) appears to beryllium falling, joined by New York Times Co (-5.5%), Paycom (-4.8%), and Popular Inc (-3.88%).

Good morning. After a unsmooth week for U.S. equities -- which saw the Nasdaq decline 2.2% contempt a astonishing rally to extremity the week -- the marketplace is ticking higher this morning. Futures are pointing to a steadfast unfastened for the large indexes, which are up betwixt 0.17% and 0.68%.